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Systematic analysis of innate lymphoid cells and natural killer cells in context of HIV-1 infection

ABSTRACT: We performed bulk and single cell RNA-Seq and ATAC-Seq of CD56-, CD56dim, CD56hi NK cells and innate lymphoid cells, revealed relationship among these developmental related populations, investigated the effect of HIV-1 infection on these innate populations. These findings clarify the interrelatedness of ILC populations disrupted by HIV-1 infection and provide insight into how these functions might be restored.

ORGANISM(S): Homo sapiens

PROVIDER: GSE168212 | GEO | 2021/03/04

REPOSITORIES: GEO

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