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Gene expression analyses of COCs treated with N-Cadherin antagonist CRS-006

ABSTRACT: N-Cadherin is a cell surface protein that is critical for cell-cell adhesion and is essential for structural integrity of tissues. In the ovary, it is expressed by granulosa cells and cumulus cells junctions throughout ovarian development. Importantly, it is also present between oocyte (egg) and surround cumulus cells, and is the only physical type of communication that is present between the egg and its surrounding cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE168347 | GEO | 2024/03/04

REPOSITORIES: GEO

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Gene expression analyses of whole ovaries from mice that were treated with N-Cadherin antagonist CRS-006

Project description:N-Cadherin is a cell surface protein that is critical for cell-cell adhesion and is essential for structural integrity of tissues. In the ovary, it is expressed by granulosa cells and cumulus cells junctions throughout ovarian development. Importantly, it is also present between oocyte (egg) and surround cumulus cells, and is the only physical type of communication that is present between the egg and its surrounding cells.

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