DNA binding profile of c-FOS in experimentally-induced basal to squamous cell carcinoma transition (BST)
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ABSTRACT: Basal cell carcinoma may undergo BST spontaneously or upon Hedgehog targeting therapy. We identified that modulation of Ras/MAPK or TGFb signaling drive BST. Here, we induce Ras/MAPK and/or abrogate TGFb signaling to induce BST and examine the DNA binding profile of the AP-1 transcription factor c-FOS.
ORGANISM(S): Mus musculus
PROVIDER: GSE168374 | GEO | 2021/10/20
REPOSITORIES: GEO
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