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Epigenome-Wide Association Study of COVID-19 Severity with Respiratory Failure

ABSTRACT: Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide spectrum of disease behavior. Since DNA methylation has been implicated in the regulation of viral infections and the immune system, we performed an epigenome- wide association study (EWAS) to identify candidate loci regulated by this epigenetic mark that could be involved in the onset of COVID-19 in patients without comorbidities.

ORGANISM(S): Homo sapiens

PROVIDER: GSE168739 | GEO | 2021/04/15

REPOSITORIES: GEO

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