Single cell RNA-seq analysis of endothelial cells during diabetic atherosclerosis
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ABSTRACT: Single-cell RNA sequencing (scRNA-seq) was performed on the CD31-mircrobeads enriched endothelial cells isolated from aorta and heart from eight-week-old, male Ldlr-/- mice fed standard chow (Chow) or diabetogenic high-fat diet with 0.15% cholesterol (DDC) diet for 12 weeks. This study report the changes of EC subpopulations, fractions, transcriptomic and metabolic profiles during diabetic atherosclerosis.
ORGANISM(S): Mus musculus
PROVIDER: GSE169332 | GEO | 2021/05/04
REPOSITORIES: GEO
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