Transcriptomics

Dataset Information

0

Gene expression analysis of TSC-tubers reveals increased expression of adhesion and inflammatory factors


ABSTRACT: Cortical tubers in patients with tuberous sclerosis complex (TSC) are associated with cognitive disability and intractable epilepsy. While these developmental malformations are believed to result from the effects of TSC1 or TSC2 Gene mutations, the molecular mechanisms leading to tuber formation during brain development as well as the onset of seizures remain largely unknown. We used the Affymetrix Gene Chip platform as a genome-wide strategy to define the Gene expression profile of cortical tubers resected during epilepsy surgery compared to histologically normal perituberal tissue (adjacent to the cortical tuber) from the same patients or autopsy control tissue.

ORGANISM(S): Homo sapiens

PROVIDER: GSE16969 | GEO | 2010/02/02

SECONDARY ACCESSION(S): PRJNA117259

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2020-01-13 | GSE132955 | GEO
2010-07-30 | E-GEOD-21755 | biostudies-arrayexpress
2024-09-02 | BIOMD0000000581 | BioModels
2018-10-24 | PXD002670 | Pride
2016-07-22 | E-GEOD-74893 | biostudies-arrayexpress
| EGAS00001002485 | EGA
2010-07-30 | GSE21755 | GEO
| phs001357 | dbGaP
2023-09-04 | GSE241410 | GEO
2006-06-13 | GSE4449 | GEO