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Transcriptional profiling of CTLA-4 as well as TGFb treated CD4+ T cells vs. a Treg cell phenotype and Tconv cells

ABSTRACT: Comparison of the transcriptional profile of CTLA-4 as well as TGFb treated CD4+ T cells with a Treg cell phenotype and Tconv cells. Since CTLA-4 and TGFb have been described as regulatory T cell inducing factors, CD4+ T cells were activated in the presence of CTLA-4 as well as TGFb. The transcriptional profile of these cells was compared to untreated CD4+CD25- T cells as well as to regulatory T cells in order to determine the relationship of these treated cells to regulatory T cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE16995 | GEO | 2018/12/31

REPOSITORIES: GEO

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