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Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [scRNA-seq engrafted HSPCs]

ABSTRACT: Single cell RNA-seq analysis for WT and Fli-1 KO engrafted HSPCs (Lineage negative CD45.2+) was performed to assess changes in transcriptional output in HSPCs following Fli-1 deletion and Notch1 overexpression and to determine distribution of cells among the different hematopoietic populations.

ORGANISM(S): Mus musculus

PROVIDER: GSE171113 | GEO | 2024/04/01

REPOSITORIES: GEO

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