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RNA-Seq analysis of human M238P melanoma cells transduced with a lentivirus expressing the miR-143/145 cluster or a control lentivirus

ABSTRACT: To assess the transcriptomic response associated with upregulation of the miR-143/-145 cluster, BRAFV600E mutant human melanoma cells M238P cells were transduced for stable expression of miR-143/145 cluster or with a control vector. Forty-eight hours after transduction, cells were treated with 1 μg/mL of puromycin for one week. RNA samples were then harvested. Two independent experiments were carried out.

ORGANISM(S): Homo sapiens

PROVIDER: GSE171881 | GEO | 2021/12/29

REPOSITORIES: GEO

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The mir-143-145 cluster plays a pro-tumorigenic role in lung adenocarcinoma by promoting neoangiogenesis

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Impact of miR-143-3p and miR-145-5p overexpression on human M238P melanoma cells

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Mice heart: wild-type mice vs. alpha MHC/mir-143/145 transgenic mice

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microRNA-143/145 loss induces Ras-signaling and cooperates with Pten-deficiency to promote basal-like breast cancer [CGH]

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