Genomics

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Microarray-based clustering analysis of miRNAs altered in LPS-AKI mouse kidney


ABSTRACT: The aim of this study was to identify miRNAs that regulate AKI and develop their applications as diagnostic biomarkers and therapeutic agents. First, kidney tissues from two different AKI mouse models, namely, AKI induced by the administration of lipopolysaccharide (LPS) causing sepsis (LPS-AKI mice) and AKI induced by renal ischemia–reperfusion injury (IRI-AKI mice), were exhaustively screened for their changes of miRNA expression compared with that of control mice by microarray analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE172038 | GEO | 2021/05/14

REPOSITORIES: GEO

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