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TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity

ABSTRACT: To elucidate the molecular mechanisms by which 14-3-3ε and PGRN regulates macrophage plasticity, we performed unbiased RNA-seq on BMDMs isolated from WT, PGRN-/- and 14-3-3ε-/- mice stimulated with pro-inflammatory LPS/IFNγ or anti-inflammatory IL-4.

ORGANISM(S): Mus musculus

PROVIDER: GSE172119 | GEO | 2022/04/14

REPOSITORIES: GEO

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TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity.

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