Transcriptomics

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Characterization of cis-regulatory elements of effector ISGs


ABSTRACT: We investigated the transcriptional activation and cis-regulatory elements of effector ISGs in CD8+ murine dendritic cells (DCs) stimulated with IFN-beta. We analysed gene repression changes and characterized activated cis-regulatory regions. Binding of ISGF3 subunits (IRF9, Stat1, and Stat2) and other transcription factors, DNA motifs, and chromatin status were also determined.

ORGANISM(S): Mus musculus

PROVIDER: GSE172376 | GEO | 2022/04/01

REPOSITORIES: GEO

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