The Keap1-Nrf2-Bach1 signaling mediates UBR7 negative regulation of HK2 to inhibit glycolysis and HCC tumorigenesis
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ABSTRACT: We found that Keap1-Nrf2 signaling pathway mediates UBR7 to regulate HK2 expression through the modification of histone H2BK120 monoubiquitination, thereby inhibiting glycolysis and HCC tumorigenesis.
ORGANISM(S): Mus musculus
PROVIDER: GSE173454 | GEO | 2022/12/09
REPOSITORIES: GEO
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