Genomics

Dataset Information

0

Chromatin state changes induced by targeted degradation of MLL-AF9 are phenocopied by combined DOT1L and MENIN inhibition. [ChIP-Seq]


ABSTRACT: Using ChIP-seq we examined the occupancy changes of various histone marks and chromatin-bound proteins following accute MLL-AF9 degradation in MLL-AF9-HA-FKPB12 transformed human (HCB1) cells. We also examined occupancy changes of various chromatin-bound proteins in human MLL-AF9-HA-FKBP12 transformed cells (HCB1) and MOLM13 cells in response to DOT1L inhibition, Menin-MLL inhibition, and the combination of DOT1L and Menin-MLL inhibition.

ORGANISM(S): Homo sapiens

PROVIDER: GSE173599 | GEO | 2022/03/03

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-03-03 | GSE173574 | GEO
2022-03-03 | GSE189098 | GEO
2022-03-03 | GSE173571 | GEO
2022-03-03 | GSE189105 | GEO
2016-11-14 | GSE63664 | GEO
2019-11-06 | GSE127507 | GEO
2018-08-01 | GSE117933 | GEO
2022-11-03 | GSE216963 | GEO
2015-04-30 | E-GEOD-64365 | biostudies-arrayexpress
2015-04-30 | GSE64365 | GEO