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Transcriptome profiles of B cells from MS patients and healthy controls

ABSTRACT: How epigenetic changes contribute to MS pathogenesis is still poorly understood. Therefore, we conducted a comprehensive analysis of genome-wide DNA methylation patterns in four immune cell populations isolated from MS patients at clinical disease onset. We also performed parallel transcriptome analysis in B cells to better understand the functional consequences of the DNA methylation changes in MS.

ORGANISM(S): Homo sapiens

PROVIDER: GSE173789 | GEO | 2022/01/18

REPOSITORIES: GEO

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