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Single-cell reconstitution reveals persistence of clonal heterogeneity in the murine hematopoietic system [RNA-seq]

ABSTRACT: We transplanted a single HSC into irradiated mice, creating a clonal hematopoietic system. Using RNA-Seq on the cDNA of the peripheral compartments (T cells, B cells), we studied mitotically stable transcriptional states of the alleles of the entire transcriptome on the differentiating HSC.

ORGANISM(S): Mus musculus

PROVIDER: GSE174038 | GEO | 2022/05/20

REPOSITORIES: GEO

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Single-cell reconstitution reveals persistence of clonal heterogeneity in the murine hematopoietic system [WES]

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Single-cell reconstitution reveals persistence of clonal heterogeneity in the murine hematopoietic system

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