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Switching of OAS1 splicing isoforms mitigates SARS-CoV-2 infection

ABSTRACT: We aimed to study impact of CDC-like kinase (CLK) inhibitor CaNDY on OAS1 splicing manipulation. Our data indicates CaNDY treatment induces switching of OAS1 splice isoforms to provide an increased resistance to SARS-CoV-2 infection.

ORGANISM(S): Homo sapiens

PROVIDER: GSE174398 | GEO | 2021/08/02

REPOSITORIES: GEO

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