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Chronic mineral oil administration increased hepatic inflammation in wild type mice compared to lipocalin 2 null mice

ABSTRACT: Concerning the roles of LCN2 in chronic inflammation and fibrosis, we investigated chronic liver inflammation and fibrosis using repeated carbon tetrachloride (CCl4) in mineral oil injection. We found that mice treated with the mineral oil vehicle alone also showed liver inflammation and more severe in wild-type mice compared to lipocalin 2 null mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE176093 | GEO | 2021/09/11

REPOSITORIES: GEO

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