Transcriptomics

Dataset Information

0

Role of BHLHE40 in shaping macrophage inflammatory response


ABSTRACT: BHLHE40 is a member of basic helix-loop-helix family transcription factors and highly conserved across mammalian species. Structurally, BHLHE40 consists of an N-terminal basic DNA binding domain, a helix-loop-helix dimerization domain, and a protein interacting orange domain. BHLHE40 is known to regulate a wide variety of essential cellular processes, including cell cycle, cellular proliferation, programmed cell death, cellular development and differentiation, and circadian rhythm. Here we isolated thioglycollate-elicited peritoneal macrophages (PMs) from 3 mice per group (Lyz2cre and Lyz2cre:BHLHE40Fl/Fl). These cells were stimulated with 100ng/ml LPS for 4 hours. Total RNA was isolated and subjected to RNAseq analyses.

ORGANISM(S): Mus musculus

PROVIDER: GSE176174 | GEO | 2021/09/24

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-09-13 | GSE242900 | GEO
2023-09-13 | GSE235608 | GEO
2023-09-13 | GSE242911 | GEO
2023-09-28 | GSE244300 | GEO
2021-03-05 | GSE131364 | GEO
2023-09-04 | GSE241941 | GEO
2022-01-19 | GSE192546 | GEO
2016-01-04 | E-GEOD-75407 | biostudies-arrayexpress
2016-01-04 | GSE75407 | GEO
2018-05-03 | GSE85959 | GEO