RNA-sequencing of IRF5+ and IRF5- circulating monocytes from patients with Type-2 Diabetes
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ABSTRACT: Purpose: To characterise the transcriptomic landscape in monocytes associated with IRF5 expression Methods: RNA sequencing from FACS sorted IRF5+ and IRF5- CD14+ monocytes Results: Differential expression based on IRF5 postiivity provides insight into its roles in monocyte function and in type-2 diabetes Conclusions: This study represents the first analyses of IRF5-dependent transcriptome in circulating monocytes from patients with Type-2 diabetes
ORGANISM(S): Homo sapiens
PROVIDER: GSE176216 | GEO | 2022/07/22
REPOSITORIES: GEO
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