Transcriptomics

Dataset Information

0

The Transcriptional Response to Oxidative Stress is Independent of Stress-Granule Formation


ABSTRACT: We characterized oxidative-stress-induced transcriptional changes in Drosophila S2 cells and assessed how these were altered under conditions that disrupted stress granule (SG) assembly. Sodium-arsenite stress for 3 hours resulted predominantly in the induction or upregulation of stress-responsive mRNAs whose levels peaked during cell recovery after stress cessation. RNAi-mediated knock down of the conserved G3BP1/ Rasputin protein inhibited stress-granule assembly. However, this disruption had no significant effect on the stress-induced transcriptional response.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE178464 | GEO | 2022/01/24

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2019-12-12 | PXD011956 | Pride
2016-02-29 | E-GEOD-76814 | biostudies-arrayexpress
2021-11-25 | PXD023989 | Pride
2024-10-07 | GSE254630 | GEO
2024-10-07 | GSE254629 | GEO
2024-09-06 | GSE242462 | GEO
2023-12-13 | GSE249869 | GEO
2024-08-18 | GSE274650 | GEO
2022-06-09 | MSV000089622 | MassIVE
2024-10-07 | GSE254634 | GEO