Transcriptomics

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RNA sequencing of chronically damage human colon organoids via Air-liquid interface submergence


ABSTRACT: We report that repeated rounds of media submergence damage of human colon organoids led to the inability of cells to regrow and respond appropriately to TLR stimulation. We also identified mRNA expression and DNA methylation changes in genes associated with IBD and colon cancer.

ORGANISM(S): Homo sapiens

PROVIDER: GSE178698 | GEO | 2021/06/23

REPOSITORIES: GEO

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