Transcriptomics

Dataset Information

0

Effects of amiloride in lithium induced kidney interstitial fibrosis


ABSTRACT: Purpose: The goal of this study is to understand the role of co-administred amiloride. This was derived through RNAseq of kidney cortex and determining differential genes in response to lithium, lithium+amiloride and control at 14 days, 28 days and 6 months. Methods: RNAseq of kidney cortex treated with either lithium alone, lithium+amiloride or control. Deseq2 was performed using contrast argument with Wald test to identify significant differentially expression genes at each time point individually. Result & Conclusion: Co-administration with amiloride at all time points contributed in the reduction of inflammation and fibrosis caused by lithium.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE178950 | GEO | 2022/08/31

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-08-31 | GSE178695 | GEO
| PRJNA741543 | ENA
2019-07-01 | PXD010118 | Pride
2022-06-09 | GSE205422 | GEO
2015-03-16 | GSE66276 | GEO
| PRJNA740023 | ENA
2018-09-10 | GSE95077 | GEO
2017-01-26 | E-MTAB-4611 | biostudies-arrayexpress
2013-02-02 | GSE34747 | GEO
2011-03-31 | E-GEOD-24581 | biostudies-arrayexpress