Genomics

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Transcriptional programs dictating Schwann cell transformation in MPNST [scATACseq]


ABSTRACT: We used single-cell RNAseq to profile early and advanced mouse MPNST tumors, as well as human neurofibroma and MPNST. Our work defines the stage-specific kinetics of transcriptomics, cellular heterogeneity, and tumor cell fate decisions in murine and human MPNSTs.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE178988 | GEO | 2022/11/07

REPOSITORIES: GEO

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