Differentially expressed genes in CSRP2BP knockdown HTR-8 cells
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ABSTRACT: CSRP2BP plays an important role in cell cycle progression, apoptosis and mammalian development, CSRP2BP knockdown by specific shRNA (CSRP2BP-shRNA) significantly inhibited the proliferation, migration, and invasion of HTR-8 trophoblast cells, and placental explant outgrowth, while CSRP2BP overexpression did the opposite. To elucidate the mechanisms by which CSRP2BP regulated the function of trophoblast cells, we performed microarray analysis to compare the transcription profiling between the HTR-8-shNC and HTR-8-shCSRP2BP cells
ORGANISM(S): Homo sapiens
PROVIDER: GSE179177 | GEO | 2021/07/01
REPOSITORIES: GEO
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