Transcriptomics

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Exploration of genes involved in mature B cells-directed inflammation caused by PTEN mutation


ABSTRACT: To expose additional genes and signaling pathways involved in the B cell-mediated inflammation in CD23-cKO mice, we performed single-cell RNA-sequencing (scRNA-seq) transcriptomic analysis. These data suggest that the induction of TLR9-mediated IL-6 production triggered by PTEN deficiency relies on BCR-directed endocytosis.

ORGANISM(S): Mus musculus

PROVIDER: GSE179715 | GEO | 2024/07/08

REPOSITORIES: GEO

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