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CLIP-seq analysis of KSHV ORF57-associated RNAs


ABSTRACT: Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 is a viral RNA-binding protein essential for viral lytic gene expression. ORF57 binds to target RNA directly via interaction with cellular cofactors. To investigate the entire repertoire of ORF57-associated RNAs we performed UV cross-linking immunoprecipitatin (CLIP) experiment using an affinity-purified, highly specific anti-ORF57 antibody in KSHV-infected primariy effusion lymphoma BCBL-1 cells undegoing lytic virus replication.

ORGANISM(S): Homo sapiens

PROVIDER: GSE179726 | GEO | 2021/11/08

REPOSITORIES: GEO

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