Transcriptomics

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Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPS cells (SPC positive cells)


ABSTRACT: We generated iPSCs from HPS1 patient-derived fibroblasts with bi-allelic c.1472_1487dup16 variant in HPS1 gene and their gene-corrected ones and differentiated them into alveolar epithelial cells in organoids for disease modeling of HPS1.

ORGANISM(S): Homo sapiens

PROVIDER: GSE179898 | GEO | 2021/11/04

REPOSITORIES: GEO

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