Transcriptomics

Dataset Information

0

Transcriptome analysis of human colonic organoids infected SARS-CoV-2


ABSTRACT: Purpose: To identify the diferentially expressed genes in SARS-CoV-2 susceptible and resistant organoids during the ifnection. Method: We selected 3 susceptible (C8, C9, and C10)- and 3 restant (C1, C2, and C7)-organoids lines and infected SARS-CoV-2 at multiplicity of infection (MOI) of 4 for 24 and 72 hrs. The RNAs were collected and then sequenced by CEL-seq2. Sequencing was performed on Illumina NovaSeq 6000. Results: Longitudinal transcriptome analyses identified robust yet late transcriptional changes induced by SARS-CoV-2, the magnitude of which corresponded to the levels of viral infection.

ORGANISM(S): Homo sapiens

PROVIDER: GSE179949 | GEO | 2022/02/16

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-07-14 | GSE237059 | GEO
2022-01-23 | GSE149687 | GEO
2020-10-01 | GSE153684 | GEO
2021-09-20 | GSE184390 | GEO
2020-05-01 | GSE149312 | GEO
2021-06-08 | GSE152060 | GEO
2021-08-07 | GSE155974 | GEO
2024-11-20 | GSE279753 | GEO
2020-10-27 | GSE152586 | GEO
2014-10-31 | E-GEOD-52920 | biostudies-arrayexpress