Genomics

Dataset Information

0

Confined Migration Induces Heterochromatin Formation and Alters Chromatin Accessibility


ABSTRACT: We show that confined migration results in predominantly decreased chromatin accessibility, consistent with the increased heterochromatin marks staining. A small fraction of ATAC-seq peaks shows increased accessibility at gene promoters of diverse pathways, such as chromatin silencing, tumor invasion, and DNA damage response; whereas the majority shows decreased accessibility at intergenic regions near centromeres or telomeres, suggesting possible heterochromatin spreading.

ORGANISM(S): Homo sapiens

PROVIDER: GSE181247 | GEO | 2022/08/10

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| PRJNA751211 | ENA
2013-09-24 | E-GEOD-46430 | biostudies-arrayexpress
2009-08-01 | GSE16742 | GEO
2013-09-24 | GSE46430 | GEO
2022-11-02 | PXD032944 | Pride
2015-05-01 | E-GEOD-46462 | biostudies-arrayexpress
2015-09-10 | E-GEOD-51682 | biostudies-arrayexpress
2015-05-22 | E-GEOD-61688 | biostudies-arrayexpress
2024-01-14 | GSE193383 | GEO
2022-08-24 | GSE198675 | GEO