Transcriptomics

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Punctual ablation of Foxp3+ T cells unleashes an autoimmune lesion


ABSTRACT: How do Treg cells control an autoimmune lesion? We depleted Foxp3+ Treg cells in autoimmune prone TCR transgenic BDC2.5 mice on the NOD background Kinetic of gene-expression changes in CD4 T cells isolated for pancreas and pancreas draining lymph node (PLN) of Foxp3-DTR.BDC2.5/NOD mice after Treg cell ablation Keywords: T cell activation/ differentiation after Treg depletion timecourse

ORGANISM(S): Mus musculus

PROVIDER: GSE18136 | GEO | 2009/10/15

SECONDARY ACCESSION(S): PRJNA119423

REPOSITORIES: GEO

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