Punctual ablation of Foxp3+ T cells unleashes an autoimmune lesion
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ABSTRACT: How do Treg cells control an autoimmune lesion? We depleted Foxp3+ Treg cells in autoimmune prone TCR transgenic BDC2.5 mice on the NOD background Kinetic of gene-expression changes in CD4 T cells isolated for pancreas and pancreas draining lymph node (PLN) of Foxp3-DTR.BDC2.5/NOD mice after Treg cell ablation Keywords: T cell activation/ differentiation after Treg depletion timecourse
ORGANISM(S): Mus musculus
PROVIDER: GSE18136 | GEO | 2009/10/15
SECONDARY ACCESSION(S): PRJNA119423
REPOSITORIES: GEO
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