Genomics

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The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis [ATAC-seq]


ABSTRACT: The purpose of this study was to decipher the molecular function of ARID3A. We leveraged gene expression (RNA-Seq) and chromatin profiling (ATAC-Seq and CUT&RUN) to evaluate gene expression changes upon restoring Arid3a expression in the context of the Gata1s mutation and miR-125b overexpression

ORGANISM(S): Mus musculus

PROVIDER: GSE181569 | GEO | 2022/04/20

REPOSITORIES: GEO

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