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Dynamic transcriptome and chromatin architecture in granulosa cells during chicken folliculogenesis

ABSTRACT: Ovarian follicle development is a complex and well-orchestrated biological process. Granulosa cells (GCs) are the most important somatic cells in the ovary, which play important roles in the growth of follicles. Three-dimensional (3D) chromatin architecture has emerged as an important regulator of transcription in eukaryote, but how these changes in granulosa cells during folliculogenesis of chicken are largely unexplored. Here, we performed an integrative analysis of transcriptomic and chromatin structural characterization for chicken follicular granulosa cells of 10 and 3 growth stages respectively.

ORGANISM(S): Gallus gallus

PROVIDER: GSE181756 | GEO | 2021/11/10

REPOSITORIES: GEO

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