RNA-sequencing for the characterization of the transcriptome of MCF-7-derived mammospheres and parental breast cancer cells.

ABSTRACT: RNA-sequencing was performed in MCF-7-derived mammospheres and parental breast cancer cells in an effort to identify novel regulators of stemness that could potentially be targeted in luminal ER+ tumors. The bioinformatic analysis identified numerous differentially expressed genes including several known stemness markers, as well as novel genes that may play an important role in breast cancer stem cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE182532 | GEO | 2021/10/27

REPOSITORIES: GEO