Transcriptomics

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TIPE1 regulation on macrophage polarization


ABSTRACT: Macrophages perform key and distinct functions in maintaining tissue homeostasis through finely tuning their polarization state.Here, we found that tumor necrosis factor-α-induced protein 8-like 1 (TIPE1) was highly expressed in macrophages and Tipe1 depletion impeded M2 polarization of macrophages. The goals of this study are to compare BMDMs from LyzM-Cre; Tipe1f/f or Tipe1f/f mice to have a further view of the potential difference.

ORGANISM(S): Mus musculus

PROVIDER: GSE183208 | GEO | 2021/09/05

REPOSITORIES: GEO

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