Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq results of the kidney of male kidney-specific G9a knockout mice after acute kidney injured

ABSTRACT: To understand key pathways and regulatory genes in male Kidney-specific G9a knockout mice after renal ischemia reperfusion

ORGANISM(S): Mus musculus

PROVIDER: GSE183455 | GEO | 2023/04/09

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNA-seq results of the kidney of male kidney-specific G9a knockout mice after acute kidney injured

Project description:RNA-seq results of the kidney of male kidney-specific G9a knockout mice after acute kidney injured

| PRJNA760905 | ENA

Expression data from injured murine kidney

Project description:Renal recovery following injury relies on cellular regeneration. In the mouse kidney following injury, injured epithelial cells undergoes de-differentiate, proliferate and re-differentiate into functional cells, following a a tightly controlled genetic programme where specific sets of genes are up-regulated. We used microarrays to detail the global programme of gene expression underlying cellular regeneration following injury with or without a HDAC inhibitor, m4PTB, treatment and identified distinct classes of up-regulated genes during this process. Male BALB/c mice underwent 26 minute unilateral ischemia-reperfusion (IR) with contralateral nephrectomy treated with vehicle or 100 mg/kg m4PTB 24 h after inducing renal injury, and kidneys harvested for RNA extraction 12 h later. We sought to obtain kidneys within a similar degree of injury in order to carefully evaluate the effect of m4PTB on expression profiles. To that end, we selected kidneys according to three different criteria of injury: (1) level of serum creatinine at Day1, (2) the level of blood urea nitrogen (BUN) (3) Kim1 expression by qPCR at Day1.5 using haevested kidneys

2013-03-01 | E-GEOD-42247 | biostudies-arrayexpress

RNA-seq results in the kidney of female Tet1 knockout mice treated with or without ischemia reperfusion

Project description:To understand key pathways and regulatory genes in the kidney of female Tet1 knockout mice treated with ischemia reperfusion

2023-11-08 | GSE232751 | GEO

Effect of tubular IKKb deletion in acute ischemic kidney injury

Project description:To establish the role of Ikkb during acute kidney injury, we use a mouse line with a specific deletion of Ikkb in the renal tubular system and exposed them to ischemia/reperfusion. Sample collection were done 2 days and 14 days after ischemia/reperfusion.

2022-07-09 | GSE207430 | GEO

Gene expression in kidney cells after unilateral ischemia-reperfusion

Project description:To determine changes in gene expression due to ischemia-reperfusion AKI in different intra-renal cell populations

2024-04-17 | GSE263369 | GEO

Mouse kidney ischemia-reperfusion injury time course

Project description:Time course experiments involving bilateral renal ischemia reperfusion injury (IRI) in C57BL/6J mice (0 hr control, 20 min bilateral ischemia without reperfusion, 4, 16, 24, 36, 48, and 72 hrs post IRI). This dataset also includes IRI at 48 hrs and 72 hrs in Azin1 A-to-I locked and Azin1 A-to-I uneditable mice.

2024-09-30 | GSE267650 | GEO

RNA microarray of rat kidney treated with or without silicon nano-particles against ischemia reperfusion injury

Project description:RNA microarray was performed to evaluate the efficacy of silicon nano-particles on renal transcriptomes of rats against ischemia reperfusion injury. We compared the transcriptomes of ischemia reperfusion injury model rats with or without oral administration of silicon nano-particles. We also tried to check whether the oral silicon nano-particles intake downregulated the biological processes related to oxidative stress.

2020-02-04 | E-MTAB-8687 | biostudies-arrayexpress

miRNA profiling of urinary exosomes to assess the progression of acute kidney injury

Project description:Using renal ischemia-reperfusion injury as a model of acute kidney injury, we deteremined temporally-released miRNAs released in urinary exosomes during the injury

2019-01-05 | GSE124669 | GEO

Effects of Poly (ADP-ribose) Polymerase Inhibitor Treatment on the Repair Process of Ischemic Acute Kidney Injury

Project description:The role of PARP inhibitors in the repair process of renal remains unclear. The effects of JPI-289, a novel PARP inhibitor, during the healing phase after renal ischemia-reperfusion injury were investigated.

2023-08-03 | GSE239905 | GEO

Aortic gene expression after acute kidney injury

Project description:The risk of cardiovascular events rises after acute kidney injury. Leukocytes promote atherosclerotic plaque growth and instability. We here established a model of enhanced remote atherosclerosis after renal ischemia reperfusion injury and investigated the underlying inflammatory mechanisms.

2022-04-13 | GSE193275 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data