Effect of Lactobacillus plantarum MB452 on the gene expression of the intestinal epithelial cell line Caco-2
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ABSTRACT: The hypothesis of this research was that probiotic bacteria that increase intestinal barrier function achieve this, partly, by increasing the expression of the genes involved in tight junction signalling in healthy intestinal epithelial cells. L. plantarum MB452 isolated from the probiotic product VSL#3 was chosen as the test bacterium because it has a robust, repeatable, positive effect tight junction integrity, as measured by the trans-epithelial electrical resistance (TEER) in vitro.
ORGANISM(S): Homo sapiens
PROVIDER: GSE18372 | GEO | 2009/10/07
SECONDARY ACCESSION(S): PRJNA118139
REPOSITORIES: GEO
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