Landscape and age dynamics of immune cells in the Egyptian Rousette Bat
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ABSTRACT: Bats harbor high-impact zoonotic viruses in absence of clinical disease, which has been recently associated with unique features of their immune system. They seem to restrict inflammation and possibly limit disease manifestation to a minimum. In-depth characterization of cellular immunity in bats is yet largely missing, and imprinting of age and development on immune cell compartments remains unexplored. We employed single-cell transcriptomics and established immunostaining panels to investigate the immune cell populations peripheral blood for juvenile and adult Egyptian Rousette bats (ERB).
ORGANISM(S): Rousettus aegyptiacus
PROVIDER: GSE183925 | GEO | 2022/07/21
REPOSITORIES: GEO
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