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Exosomal microRNA sequencing in Tongxinluo pretreated and non-treated MSC-derived exosomes

ABSTRACT: In order to investigate the specific mechanisms underlying the cardioprotective effects of Tongxinluo pretreated MSC-derived exosomes (MSCTXL-Exo) in cardiac repair, we performed microRNA sequencing on exosomes secreted from Tongxinluo pretreated MSCs and non-treated MSCs to identify differentially expressed miRNA. We found that 18 miRNAs were identified to be upregulated and 25 miRNAs downregulated (over 2-fold change) in MSCTXL-Exo compared to MSC-Exo.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE184067 | GEO | 2022/06/01

REPOSITORIES: GEO

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