Transcriptomics

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Duper is a Cryptochrome 1 null mutation in Syrian hamsters


ABSTRACT: The duper mutation is a recessive mutation that shortens the period length of the circadian rhythm in Syrian hamsters. These animals show a large phase shift when responding to light pulses. Using two distinct ecotypes and a fast homozygosity mapping strategy, we identified duper as an early nonsense allele of Cryptochrome 1 (Cry1) leading to a short, unstable protein.

ORGANISM(S): Mesocricetus auratus

PROVIDER: GSE184205 | GEO | 2022/04/18

REPOSITORIES: GEO

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