Dissecting the process of human neutrophil lineage determination by using alpha-lipoic acid inducing neutrophil deficiency model
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ABSTRACT: Neutrophil deficiency or differentiation disorder might cause serious diseases, such as neutropenia and neutrophilia. To reveal the molecular mechanism of human neutrophil lineage commitment, single cell RNAseq and bulk cells RNAseq were performed to reveal the characteristics and essential genes of neutrophil lineage determination.
ORGANISM(S): Homo sapiens
PROVIDER: GSE184864 | GEO | 2022/07/20
REPOSITORIES: GEO
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