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Transcriptome profiling of H3K27me3 demethylase deficient B cells

ABSTRACT: To assess how H3K27me3 demethylases, UTX and JMJD3, regulate B cell and plasma cell trasncriptomes. RNA-seq was performed on the following populations from control (CreCtrl) and double knockout (dKO) mice: 1) naïve marginal zone B (MZB) cells and follicular B (FOB) cells from control (CreCtrl) and double knockout (dKO) mice, 2) PC generated after three days of ex vivo culture of MZB or FOB cells, 3) PC generated at three days post in vivo stimulation with LPS

ORGANISM(S): Mus musculus

PROVIDER: GSE185095 | GEO | 2022/02/01

REPOSITORIES: GEO

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Accessible chromatin profiling of H3K27me3 demethylase deficient B cells

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UTX and JMDJ3 regulate NKT development

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