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Gene expression profiling in ninaE wild type and ninaE G69D/+ Drosophila photoreceptors

ABSTRACT: Cell type specific gene expression profiling was performed with adult Drosophila photoreceptors. Two genotypes were compared: ninaE wild type control and ninaEG69D/+ mutants that have chronic endoplasmic reticulum stress. To specifically isolate RNAs from these cell types, we drove nuclear envelope-localized EGFP::Msp300KASH expression with the photoreceptor specific Rh1-Gal4 driver. Anti-GFP beads were used to isolate the nuclei from those adult fly photoreceptor cells. Novaseq was used to perform RNA-seq.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE185134 | GEO | 2021/10/02

REPOSITORIES: GEO

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