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RNASeq analysis of human Cal33 xenografts in nu/nu mice upon radiotherapy +/- metformin treatment

ABSTRACT: Purpose: We aim to identify transciptional changes of Cal33 xenografts upon radiotherapy +/- metformin treatment in vivo Method: Cal33 cells were heterotopically transplanted onto NMRI nude mice and subjected to fractionated irradiation with 5x 2 Gy ± 5x 250 µg/g metformin treatment starting on d4 after inoculation. After 5 days of therapy, tumors were explanted, total RNA was extracted, and subjected to RNAseq analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE185624 | GEO | 2022/01/11

REPOSITORIES: GEO

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