Genomics

Dataset Information

0

Genome-wide identification of transcriptional targets for H4K12la in total brain cells and microglia of WT and 5XFAD mice


ABSTRACT: In this study, we found that H4K12la level is elevated in plaque-adjacent microglia of 5XFAD mice. To further explore the potential functional significance of H4K12la in AD, we performed genome-wide cleavage under targets and tagmentation (CUT&Tag) analysis to identify candidate genes regulated by H4K12la in total brain cells and microglia. Following CUT&Tag, H4K12la-associated DNAs were amplified using non-biased conditions, labeled, and sequenced with Illumina NovaSeq 150PE.

ORGANISM(S): Mus musculus

PROVIDER: GSE188765 | GEO | 2022/01/20

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-10-24 | GSE245752 | GEO
2023-10-29 | GSE240006 | GEO
2024-10-28 | GSE277724 | GEO
2024-06-01 | GSE242113 | GEO
2024-05-01 | GSE266243 | GEO
2024-05-01 | GSE266242 | GEO
2023-10-29 | GSE240005 | GEO
2022-07-17 | GSE208202 | GEO
2023-06-01 | GSE231403 | GEO
2021-03-04 | GSE168137 | GEO