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Transcriptomic profile of liver fibrosis in mice induced by CCl4

ABSTRACT: This study is aimed to investigate the underlying mechanisms of didymin on anti-hepatic fibrosis. In brief, mice were randomly devided into three groups,including normal, CCl4 and didymin groups. Except the normal group, mice were intra-peritonelly administrated with 20% CCl4 for 10 weeks to induce liver fibrosis; after modeling successfully, mice in didymin group were subsequently intragastrically administrated with didymin for 6 weeks. Finally, the transcriptomic analysis was performed to acquire the differently expressed genes amog the three groups, trying to figure out the potential targets, which regulated by didymin.

ORGANISM(S): Mus musculus

PROVIDER: GSE189409 | GEO | 2021/11/25

REPOSITORIES: GEO

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