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Epigenome analysis of ALKBH5 knocked down HCT116 cell

ABSTRACT: ALKBH5 is one of the important m6A demethylases and is reported to be closely associated with tumorigenesis.In this study, we investigated whether ALKBH5 could affect genome-wide DNA methylation pattern. We investigated DNA methylation profile of ALKBH5 deleted HCT116 cell with control cell. The Illumina Infinium HumanMethylation 850K BeadChip was used. Samples included 2 HCT1116 shNC and 4 HCT116 shALKBH5.

ORGANISM(S): Homo sapiens

PROVIDER: GSE190375 | GEO | 2024/12/07

REPOSITORIES: GEO

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