Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single cell RNA-Seq of blood cells in irradiated patient

ABSTRACT: This study aims to explore mRNA expression of irradiated people’s blood by single cell RNA-Seq. In this study, the blood was isolated from patients. The blood of irradiated patient was collected from a patient who exposed to irradiated.

ORGANISM(S): Homo sapiens

PROVIDER: GSE190439 | GEO | 2024/12/06

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Single-cell RNA-Seq of blood cells between an irradiated patient and non-irradiated healthy men

Project description:This study aims to compare mRNA expression between irradiated and non-irradiated people’s blood by single-cell RNA-Seq. In this study, the blood was isolated from patients or healthy persons. The Control group of blood were collected from ten different persons without radiation and mixed for RNA-seq. The blood of irradiated patient was collected from a patient who was exposed to radiation.

2021-08-11 | GSE166902 | GEO

Single cell RNA-Seq of blood cells in an irradiated patient

Project description:This study aims to explore the cell clusters and mRNA expression at the single cell level in a irradiated patient. The patient was a nuclear accident patient exposed to an X-ray fluorescence spectrometer. In this study, the blood of irradiated patient was collected from a patient who was exposed to irradiated.

2025-01-19 | GSE194104 | GEO

Single cell RNA-Seq analysis of irradiated and non-irradiated skin cells in a nuclear accident patient.

Project description:This study aims to compare mRNA expression between irradiated and non-irradiated people’s skin by single cell RNA-Seq.The patient was a nuclear accident patient exposed to an X-ray spectrometer. In this study, the skin tissues was isolated from patient's different parts. The Control group of skin was collected from the patient belly without radiation for RNA-seq. The skin of IR group was collected from the irradiated skin tissue on the right hand of patients during skin grafting.

2024-10-02 | GSE193807 | GEO

Single cell RNA-Seq of blood cells in irradiated patient

Project description:Single cell RNA-Seq of blood cells in irradiated patient

| PRJNA787206 | ENA

Single cell RNA-Seq of blood cells in an irradiated patient

Project description:Single cell RNA-Seq of blood cells in an irradiated patient

| PRJNA799053 | ENA

Single-cell RNA-Seq of blood cells between an irradiated patient and non-irradiated healthy men

Project description:Single-cell RNA-Seq of blood cells between an irradiated patient and non-irradiated healthy men

| PRJNA702194 | ENA

Single cell RNA-Seq analysis of irradiated and non-irradiated skin cells in a nuclear accident patient.

Project description:Single cell RNA-Seq analysis of irradiated and non-irradiated skin cells in a nuclear accident patient.

| PRJNA798020 | ENA

Analysis of mRNA expression between irradiated and non-irradiated keloid-derived primary cells.

Project description:This study aims to compare mRNA expression between irradiated and non-irradiated keloid-derived primary cells by RNA-Seq. In this study, keloid-derived primary cells that were isolated from patients, and then divided into three groups and each group had four repeats. The first group of cells was treated without radiation, the second group of cells were received 4 Gy delivered in 2-Gy fractions once per day over 2 days and the third group of cells were received 8 Gy delivered in 2-Gy fractions once per day over 4 days.The last two groups of cells were irradiated at a fixed rate of 1.15 Gy/min using an X-ray linear accelerator (Rad Source Technologies Inc., Suwanee, GA, USA). 24 hours post irradiation of the third group of cells, all keloid-derived primary cells were collected and subjected to mRNA expression analysis.

2020-07-11 | GSE154234 | GEO

Taurine ameliorates oxidative stress of BMSCs and promotes osteogenesis in irradiated jaws

Project description:Osteoradionecrosis of the jaw (ORNJ) is a complication after head and neck radiotherapy that severely affects patients’ quality of life. Currently, an overall understanding of microenvironmental factors of ORNJ is still lacking. Here, we reveal the activation of taurine metabolism in irradiated mandibular stromal cells with scRNA-Seq and the decrease of taurine in irradiated bone marrow mesenchymal stromal cells (BMSCs) with metabolomics. Compared to the unirradiated BMSCs, the taurine uptake of irradiated BMSCs increases. The taurine concentration in peripheral blood and jaws of irradiated mice are significantly lower than the unirradiated mice. Supplementation of taurine promotes osteogenic differentiation, decreases oxidative stress and DNA damage of irradiated BMSCs. Oral administration of taurine significantly promotes survival rate of irradiated mice and promotes osteogenesis of irradiated jaws. Our study sheds light on the role of taurine during the recovery of radiation-induced jaw injury, suggesting a potential non-invasive therapeutic means to combat ORNJ.

2024-07-08 | MTBLS10284 | MetaboLights

Systemic Lupus Erythematosus patient blood with controls

Project description:Systemic Lupus Erythematosus patient blood with controls

| PRJNA439269 | ENA