Transcriptomics

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Single-cell RNA-seq reveals the midkine-mediated immune microenvironment dysfunction in human keloids fibrotic niche


ABSTRACT: A keloid scar is recognized as the most intractable skin pathological scar due to its continuous overgrowth, invasion of adjacent boundary and high recurrence rate. Heterogeneity of fibroblasts or vascular endothelial cells was previously characterized, while the immune microenvironment within this fibrotic niche remains largely unknown.

ORGANISM(S): Homo sapiens

PROVIDER: GSE191067 | GEO | 2024/11/25

REPOSITORIES: GEO

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