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The human dental apical papilla promotes spinal cord repair through a paracrine mechanism

ABSTRACT: Traumatic spinal cord injury is an overwhelming condition that strongly and suddenly impacts the patient’s life and her/his entourage. There are currently no predictable treatments to repair the spinal cord, while many strategies are proposed and evaluated by researchers throughout the world. One of the most promising avenues is the transplantation of stem cells, although its therapeutic efficiency is limited by several factors, among which cell survival at the lesion site. In our previous study, we showed that the implantation of a human dental apical papilla, residence of stem cells of the apical papilla (SCAP), supported functional recovery in a rat model of spinal cord hemisection.

ORGANISM(S): Homo sapiens

PROVIDER: GSE191140 | GEO | 2021/12/20

REPOSITORIES: GEO

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